Metabolic Reset, Root-Cause Care, and Aging Well with Mark Cianciolo

Dr. Jamie and Kevin sit down with Mark (a healthcare executive and N of One client) to unpack his multi-year health journey—moving from symptom-managing prescriptions to root-cause solutions. Mark shares how a 21-day metabolic reset, targeted lab work (blood and stool testing), and smart supplementation helped resolve gut issues, reduce inflammation, stabilize energy, improve sleep, and even drop 12–15 lbs as a side benefit. The conversation demystifies insulin resistance, explains why food timing and environment matter, and shows how strength training, better nutrition, and intentional recovery (massage, infrared sauna) can extend healthspan—so you can think, perform, and lead at your best.

In this episode:

• The difference between treating symptoms vs. fixing root causes
• What a 21-day metabolic reset actually looks like (and why it works)
• Labs that matter: functional bloodwork and GI testing to rule things in/out
• Insulin resistance, cravings, sleep, and inflammation—how they connect
• Personalized nutrition: discovering sensitivities (e.g., corn, pork) and re-introductions
• Building durable habits in midlife: training, recovery, and purpose-driven health

Resources mentioned: Functional medicine labs, metabolic reset protocol, binders/chelators, infrared sauna, strength training, massage therapy.